Geographic location is often a missing component in industry evolution literature whereas the time aspect is rarely considered in agglomeration studies. This paper attempts to fill this gap by evaluating the patterns of industry evolution across different regions. A historical data set for the U.S. DDT industry is created and analyzed. First, the change in the number of firms over the industry life cycle is considered, as well as the variation in the patterns of entry and exit across different regions. This part of the analysis is based on the U.S. Census division of the United States into 4 distinct regions: Northeast, Midwest, South, and West. Next, a comparison of the patterns of industry evolution in the core of the industry, where the majority of firms are located, versus its periphery is made. I find some evidence that the different regions exhibited dissimilar dynamics.